Books

LEE MLT. Analysis of Microarray
Gene Expression Data, (2004), Springer (formerly Kluwer Academic Publishers)

Mesbah M, Cole BF, LEE MLT, editors,
Statistical
Methods for Quality of Life Studies Design, Measurements and Analysis,
(2002). Springer (formerly Kluwer Academic Publishers)

Jewell NP, Kimber AC, LEE MLT, Whitmore GA , editors, Lifetime Data: Models in Reliability and
Survival
Analysis, (1996). Springer (formerly Kluwer Academic Publishers)
Peer reviewed articles in the following areas
(Last updated on 1/7/2013)

Analysis of Genomic Data

Statistical Models and Applied Probability

Applications in Epidemiology,
Environmental Studies & Microbiology
Articles in Analysis of Genomic Data
CruzCano R, Lee MLT. Fast Canonical Correlation Analysis,
Computational Statistics and Data Analysis, (Accepted, in press).
CruzCano R, Lee MLT, Leung MY. Logic Minimization and Rule Extraction for
Identification of Functional Sites in Molecular Sequences,
BioData Mining, 2012,
5:10.
PMID: 22897894
Byer SJ, Zhang X, Jimenez RE, Lee MLT, Richardson AL, Huang, Jhiang SM.
Microarray analysis of genes associated with cell surface NIS protein levels
in breast cancer.
BMC Research Notes, 2011, Vo. 4:397410. doi:
10.1186/175605004397PMID: 21989294
Lee MLT. Molecular genesignatures and cancer clinical trials, In: Designs for Clinical Trials: Perspectives on Current Issues. David Harrington, Editor,
2011, 139155.
Hunter MP, Ismail N, Zhang X, Aguda BD, Lee EJ, Yu L, Xiao T, Schafer J, Lee MLT, Schmittgen TD, NanaSinkam SP, Jarjoura D, Marsh C. Detection of microRNA Expression in Human Peripheral Blood Microvesicles, PLoS ONE, 2008, Vol. 3: 11, e3694. PMID: 19002258
Zhang Y, Bertolino A, Fazio L, Blasi G, Rampino A, Romano R, Lee MLT, Xiao T, Papp A, Wang D, and Sadée W. Novel polymorphisms in the human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory, Proceedings of the National Academy of Sciences, USA, 2007, 104: 2055220557.PMID:
18077373
Qiu W, Lee MLT. SPCalc: A webbased calculator for sample size and power calculations in microarray studies, Bioinformation, 2006, 1: 251252.PMID:
17597901
Qin S, Qiu W, Ehrlich JR, Ferdinand AS, Richie JP, O扡eary MP, Lee MLT, Liu BCS. Development of a reverse capture autoantibody microarray for studies of antigenautoantibody profiling.
Proteomics, 2006, 6: 31993209.PMID: 16596707
Lee MLT, Whitmore GA, Bjorkbacka H, Freeman M. Nonparametric Methods for Microarray Data Based on Exchangeability and Borrowed Power.
Journal of Biopharmaceutical Statistics, 2005, 15: 783797.PMID:
16078385
Tsai PW, LEE MLT. Splitplot microarray experiments: issues of design,
power and sample size. Applied Bioinformatics, 2005, 4: 187194. PMID:
16231960
Lee MLT, Gray RJ, Bjorkbacka H, Freeman MW. Generalized
Rank Tests for Replicated Microarray Data. Statistical Applications
in Genetics and Molecular Biology, 2005, Vol. 4: No. 1, Article 3.
PMID: 16646848
Lee MLT, Whitmore GA. Intensitydependent normalization in microarray
analysis: a note of concern. Bernoulli,
2004, 10: 943949.
Lee MLT, Whitmore GA, Yukhananov RY. Analysis
of unbalanced microarray data, Journal of Data
Science, 2003; 1: 103121.
Lee MLT, Whitmore GA. Power and sample size for microarray studies,
Statistics in Medicine, 2002; 21: 35433570. PMID:
12436455
Lee MLT, Bulyk ML, Whitmore GA, Church GM. A statistical model for investigating
binding probability of DNA nucleotide sequences using microarrays, Biometrics,
2002; 58: 981988. PMID: 12495153
Lee MLT, Lu W, Whitmore GA, Beier D. Models for microarray gene expression
data, Journal of Biopharmaceutical Statistics, 2002;
12: 119.
Lee MLT, Kuo FC, Whitmore GA, Sklar J. Importance of replication
in microarray gene expression studies: statistical methods and evidence
from repetitive cDNA hybridization. Proceedings of the National Academy of Sciences,
2000; 97: 98349839. PMID: 10963655
Articles in Statistical Models and Applied Probability
Statistical
Models
Whitmore GA, Zhang G, Lee MLT. Constructing normalcy and discrepancy indexes
for birth weight and gestational age using a threshold regression mixture model.
Biometrics, 2012, 68: 297306. PMID: 21838731
Xiao T, Whitmore GA, He X, Lee MLT. Threg: a new command to implement
threshold regression model in STATA.
The STATA Journal,
2012, 12(2): 257283.
Li L, Lee MLT. Analysis of Failure Time Using Threshold Regression with Semiparametric Varying Coefficients. Statistica Neerlandica,
2011, 65: 164182.
Lee MLT, Whitmore GA, Rosner B. Threshold Regression for Survival Data with Timevarying Covariates. Statistics in Medicine, 2010, 29, 78: 896  905.
PMID: 20213704
Lee MLT, Whitmore GA. Proportional hazards and threshold regression: their theoretical and practical connections.
Lifetime Data Analysis, 2010, 16, 2: 196214.
PMID: 19960249
Pennell M, Whitmore GA, Lee MLT. Bayesian random effects threshold
regression with application to survival data with nonproportional
hazards. Biostatistics, 2010, 11, 1: 111126.PMID:
19828558
Yu Z, Tu W, Lee MLT. A Semiparametric Threshold Regression Analysis of Sexually Transmitted Infections in Adolescent Women. Statistics in Medicine, 2009, 28:30293042.
PMID: 19691037
Lee MLT, Whitmore GA, Chang M. A Threshold Regression Mixture Model
for Assessing Treatment Efficacy in a Multiple Myeloma Clinical Trial. Journal of Biopharmaceutical Statistics, 2008, 18: 11361149.
PMID: 18991113
Tong X, He X, Sun J, and Lee MLT. Joint analysis of current status
and marker data: an extension of a bivariate threshold model. The International Journal of Biostatistics, 2008, Vol. 4: Iss. 1, Article 21.
PMID: 20231913
Lee MLT. Lifetime models and risk assessment.
Encyclopedia of Quantitative Risk Assessments,
Published Online in 2008. DOI: 10.1002/9780470061596.risk0478
Lee MLT, Whitmore GA. Threshold regression for survival analysis:
modeling event times by a stochastic process reaching a boundary. Statistical Sciences, 2006, 21: 501513.
Rosner B, Glynn RJ, Lee MLT. Extension of the Rank Sum Test for
Clustered Data: TwoGroup Comparisons with Group Membership Defined at
the Subunit Level. Biometrics, 2006, 62: 12511259.
PMID: 17156300
Rosner B, Glynn RJ, Lee MLT. The Wilcoxon Signed Rank Test for Paired Comparisons of Clustered Data. Biometrics, 2006, 62: 185192.
PMID: 16542245
Lee MLT, Dehling HG. Generalized twosample Ustatistics for clustered
data. Statistica Neerlandica, 2005, 59: 313323.
Shubina M., Lee MLT. On maximum attainable correlation for Sarmanov family
of bivariate distributions with equal marginal distributions, Communications in Statistics: Theory and Methods,
2004, 33: 10311052.
Rosner B, Glynn RJ, Lee MLT, Incorporation of clustering effects
for the Wilcoxon rank sum test: a large sample approach. Biometrics,
2003; 59: 10891098. PMID: 14969489
Lee MLT, Whitmore GA. First Hitting Time Models for Lifetime Data,
Handbook of Statistics, Volume 23: Advances in Survival Analysis, edited
by N. Balakrishnan and C.R. Rao. Elsevier, North Holland. 2003; 537543.
Fang HB, Sun J, Lee MLT, Nonparametric
survival comparisons for interval censored continuous data. Statistica
Sinica, 2002; 12: 10731083.
Lee MLT, Rosner BA. The average area under correlated ROC curves: a nonparametric
approach based on generalized twosample Wilcoxon statistics. Journal of Royal Statistical Society, series C, Applied
Statistics, 2001; 50: 337344.
Lee MLT, Schoenfeld D, Wang X, Penfornis A, Faustman D. Bayesian analysis
of case control polygenic etiology studies with missing data.
Biostatistics;
2001, 2(3): 309322. PMID: 12933541
Lee MLT, DeGruttola V, Schoenfeld D. A model for markers and latent
health status. Journal of Royal Statistical Society, Series
B, 2000; 62: 747762.
Lee MLT, Whitmore GA. Statistical inference for serial dilution assay
data. Biometrics,
1999; 55: 12151220. PMID: 11315070
Hougaard P, Lee MLT, Whitmore GA. Analysis of overdispersed count
data by mixtures of Poisson variables and Poisson processes.
Biometrics,
1997; 53: 12251238. PMID: 9423246
Williamson JM, Lee MLT. A GEE regression model for the association
between an ordinal and a nominal variable. Communications in Statistics: Theory and Methods,
1996; 25:18871901.
Lee MLT. Properties and applications of Sarmonov's family of bivariate
distributions. Communications in Statistics: Theory and Methods,
1996; 25:12071222.
Cole BF, Lee MLT, Whitmore GA, Zaslavsky AM. An empirical Bayes model
for Markov dependent binary sequences with randomly missing observations.
Journal of American Statistical Association, 1995;
90:136472.
Lee MLT. A two state Markov model. Communications in Statistics: Theory and Methods,
1994; 23:61523.
Benedetti J, Green S, Lee MLT, Crowley J. Report of the ad hoc committee
on design of experiments on double blind refereeing. Statistical Sciences,
1993; 8:31830.
Lee MLT, Gross AJ. Lifetime distributions under unknown environments.
Journal of Statistical Planning and Inferences,
1991; 29:13743.
Whitmore GA, Lee MLT. A multivariate survival distribution generated
by inverse Gaussian mixture of exponentials. Technometrics, 1991; 33:3950.
D'Agostino RB, Lee MLT, Belanger AJ, Cupples LA, Anderson K, Kannel
WB. Relation of pooled logistic regression to time dependent Cox regression
analysis: the Framingham Heart Study. Statistics in Medicine, 1990; 9:150115.
PMID: 2281238
Lee MLT. A moment test to identify uniformity. Communications in Statistics: Simulation and Computation,
1989; 18 Part B:25361.
Lee MLT. Some cross product difference statistics and a test
for trends in ordered contingency tables. Statistics and Probability Letters, 1988; 7:4146.
Block HW, Ting ML. Some concepts of multivariate dependence.
Communications in Statistics: Theory and Methods,
1981; A10(8):74962.
Applied
Probability
Limnios N, Lee MLT. Hoeffding's Inequality for Stopped Martingales and SemiMarkov Processes. Communications in Statistics: Theory and Methods,
2005, 34: 713720.
Lee MLT, Whitmore GA. Stochastic processes directed by randomized
time. Journal of Applied Probability, 1993; 30:30214.
Lee MLT, Rachev ST, Samorodnitsky G. Association of stable random
variables. Annals of Probability, 1990; 18:175964.
Lee MLT, Gross AJ. Properties of conditionally independent generalized
gamma distributions. Probability in the Engineering and Informational Sciences,
1989; 3:28997.
Lee MLT. Dependence by reverse regular rule. Annals of Probability,
1985; 13:58391.
Lee MLT. Dependence by total positivity. Annals of Probability,
1985; 13:57282.
Wang HC, Ting ML. Homogeneous Banach spaces of locally integrable
functions. Nanta Mathematica 1979; 12:6270.
Articles in Epidemiology,
Pharmarco Epidemiology, Microbiology & Environmental Studies
Epidemiology
Hoh JK, Cha KJ, Park MI, Lee MLT, Park YS. Estimating Time to Full Uterine Cervical Dilation Using Genetic Algorithm,
Kaohsiung Journal of Medical Sciences, August 2012; 28(8): 423428.PMID:
22892163
Rosner B, Glynn RJ, Lee MLT. A Nonparametric Test for Observational NonNormally Distributed Ophthalmic Data with EyeSpecific Exposures and Outcomes, Ophthalmic Epidemiology, July 2007; 14(4): 243250.
PMID: 17896304
Finkelstein JS, Lee MLT, Sowers MF, Ettinger B, Neer RM, Kelsey
JL, Cauley JA, Huang MH, Greendale GA. Ethnic variation in bone density
in premenopausal and early perimenopausal women: effects of anthropometric
and lifestyle factors, Journal of Clinical Endocrinology and Metabolism,
2002; 87: 30573067. PMID: 12107201
Finkelstein JS, Sowers MF, Greendale GA, Lee MLT, Neer RM, Cauley JA,
Ettinger B. Ethnic variation in bone turnover in pre and early perimenopausal
women: effects of anthropometric and lifestyle factors. Journal of Clinical
Endocrinology and Metabolism, 2002; 87: 30513056.PMID: 12107200
Leder BZ, Smith MR, Fallon M, Lee ML, Finkelstein JS. Effects of gonadal
steroid suppression on skeletal sensitivity to parathyroid hormone
in men. Journal
of Clinical Endocrinology and metabolism, 2001; 86: 511516. PMID:
11158001
Zaleznik DF, Rench MA, Hillier S, Krohn MA, Platt R, Lee MLT, Flores
AE, Ferriri P, Baker CJ. Invasive group B streptococcal disease in
pregnant women and neonates from diverse population groups.
Clinical
Infectious Diseases, 2000; 30:276281. PMID: 10671328
Lee MLT, Rosner BA, Weiss ST. Relationship of blood pressure
to cardiovascular death: the effects of pulse pressure in the elderly.
Annals of Epidemiology, 1999; 9: 101107. PMID:
10037553
Platt R, AdelsonMitty J, Weissman L, Zaleznik D., Lee ML, Baker CJ.
Resource utilization associated with initial hospital stays complicated
by earlyonset group B streptococcal disease. Pediatric Infectious Disease,
1999; 18: 529533. PMID: 10391183
Lee MLT, Rosner BA, Weiss ST, Vokonas PS, Gaziano JM. Predictors
of cardiovascular deaths: The Normative Aging Study19631998.
Clinical Geriatrics, 1999: 7: 7785.
Fielding JR, Griffiths DJ, Versi E, Mulkern RV, Lee MLT, Jolesz FA. MR
imaging of pelvic floor continence mechanisms in the supine and sitting positions.
American Journal of
Roentgenology, 1998; 171: 16071610. PMID: 9843296
Poteat HT, Ho GT, Lee MLT, Welch WR, Loughlin KR, Sacks DB. The utility
of patient age in evaluating prostate cancer, American Journal of Clinical
Pathology, 1997; 107: 337344. PMID: 9052385
Lee MLT, Rosner BA, Vokonas PS, Weiss ST. Longitudinal analysis of adult
male blood pressure: The Normative Aging Study, 19631992. Journal of Epidemiology & Biostatistics, 1996;
1:7987.
Hirschorn LR, Trnka Y, Onderdonk A, Lee MLT, Platt R. Epidemiology of
communityacquired clostridium difficile associated diarrhea. Journal
of Infectious Diseases, 1994; 169:12733. PMID: 8277174
Environmental Research
Lee MLT, Whitmore GA, Laden F, Hart JE, Garshick E. A CaseControl Study Relating Railroad Worker Mortality to Diesel Exhaust Exposure Using a Threshold Regression Model. Journal of Statistical Planning and Inferences, 2009, 139:16331642.
PMID: 19221608
Lee MLT, Whitmore GA, Laden F, Hart JE, Garshick E. Assessing lung cancer
risk in railroad workers using a first hitting time regression model. Environmetrics, 2004,15: 501512. PMID: 16741563
Tsaih SW, Korrick S, Schwartz J, Lee MLT, Amarasiriwardena C, Aro A, Sparrow D, Hu H. Relation of bone lead and blood lead to renal function among middleaged and elderly men: the Normative Aging Study. Environmental
Health Perspectives. 2004; 112: 117882.
Aro A, Amarasiriwardena C, Lee MLT, Kim R, Hu H. Validation of K xray
fluorescence bone lead measurements by inductively coupled plasma
mass spectrometry in cadaver legs. Medical Physics,
2000; 27: 119123. PMID: 10659745
Chuang HY, Schwartz J, Hu H, Lee MLT. Vibration perception thresholds
in workers with longterm lead exposure. Occupational and Environmental
Medicine, 2000; 57: 588594. PMID: 10935939
Tsaih SWT, Schwartz J, Lee MLT, Amarasiriwardena C, Aro A, Sparrow D,
Hu H. The independent contribution of bone and erythrocyte lead
to urinary lead among middleaged and elderly man: The Normative
Aging Study. Environmental
Health Perspectives, 1999; 107, 391396. PMID: 10210695
Chuang HY, Lee MLT, Chao KY, Wang JD, Hu H. The relationship of blood
lead levels to personal hygiene habits in lead battery workers: Taiwan,
19911997. American Journal of Industrial Medicine, 1999;
35: 595603.
PMID: 10332513
Pharmarco
Epidemiology
Choo PW, Rand CS, Inui TS, Lee MLT, Canning C, Platt R. A cohort
study of possible risk factors for overreporting of antihypertensive adherence,
BioMedical Central Cardiovascular Disorders, 2001;
1: 6. PMID: 11801191
Choo PW, Rand CS, Inui TS, Lee MLT, Canning C, Platt R. Derivation
of adherence metrics from electronic dosing records. Journal of Clinical Epidemiology,
2001; 54: 619626. PMID: 11377123
Choo PW, Rand CS, Inui TS, Lee MLT, Canning C, Platt R. A pharmacodynamic
assessment of the impact of antihypertensive nonadherence on blood
pressure control. Pharmacoepidemiology and Drug Safety, 2000; 9:
557563. PMID: 11338913
Choo PW, Rand CS, Inui TS, Lee MLT, Cain E, CordeiroBreault M, Canning
C, Platt R. Validation of patient reports, automated pharmacy records, and
pill counts with electronic monitoring or adherence to antihypertensive therapy.
Medical Care, 1999; 37: 846857. PMID: 10493464
Lee MLT, Lazarus R. Meta analysis for drug safety data with logistic
regressions. Drug Information Journal , 1997; 31: 11891193.
Microbiology
Onderdonk AB, Lee MLT, Liberman E, Delaney ML, Tuomala RE. Quantitative
microbiologic models for preterm delivery, Journal of Clinical Microbiology,
2003, 41: 10731079. PMID: 12624032
Lee MLT, DuBois A, Ross RA, Onderdonk AB. Nonlinear models for in
vitro kill kinetics for antibiotics. Journal of Biopharmaceutical Statistics, 1999;
9: 271277. PMID: 10379693
Lee MLT, Ross RA, Onderdonk AB. Statistical models for vaginal
microflora: identifying women at risk for group B streptococcus
colonization as a test of concept. Infectious Diseases in Obstetrics and Gynecology.
1997; 5: 336340. PMID: 18476181
Lee MLT, Onderdonk AB. Demonstration of subgroups among normal vaginal
microflora data. Microbial Ecology in Health & Disease, 1995;
7:10712.
Lee MLT, Ross RA, Onderdonk AB. Cluster analysis of vaginal microflora
data, Microecology and Therapy 1995; 25:324328.
Lee MLT, Ross RA, Delaney ML, Onderdonk AB. Mathematical modelling of
the vaginal microflora. Microecology and Therapy 1995; 23:1821.
Ross RA, Lee MLT, Delaney ML, Onderdonk AB. Use of continuous culture
growth systems for modelling vaginal microflora behaviour. Microecology
and Therapy 1995; 23:1617.
Ross RA, Lee MLT, Onderdonk AB. Effect of candida albricans infection
and clotrimazole treatment on vaginal microflora in an in vitro
model. Obstetrics
and Gynecology, 1995; 86:92530. PMID: 7501341
Lee MLT, Ross RA, Delaney ML, Onderdonk AB. Predicting abnormal microbial
population levels in the vaginal ecosystem. Microbial Ecology in Health & Diseases,
1994; 7:23540.
Ross RA, Lee MLT, Delaney ML, Onderdonk AB. Mixedeffects models for
predicting microbial interactions in the vaginal ecosystem. Journal of Clinical Microbiology,
1994; 32:87175. PMID: 802733
